REGULATORYRFK Jr.: 14 peptides returning to Category 1 — FDA advisory committee July 2026TRENDINGHexarelin: ↑↑ Surging ��� Trends score 100 as of May 2026UPDATESemaglutide and tirzepatide compounding ended — shortage resolved Feb/May 2025REGULATORYBPC-157, TB-500, thymosin alpha-1, CJC-1295, ipamorelin: expected Category 1 reclassification pendingEVENTpep-talk con ��� First US Peptide Convention · August 2026 · Anaheim CAFDAFDA advisory committee meetings scheduled: late July 2026REGULATORYRFK Jr.: 14 peptides returning to Category 1 — FDA advisory committee July 2026TRENDINGHexarelin: ↑↑ Surging ��� Trends score 100 as of May 2026UPDATESemaglutide and tirzepatide compounding ended — shortage resolved Feb/May 2025REGULATORYBPC-157, TB-500, thymosin alpha-1, CJC-1295, ipamorelin: expected Category 1 reclassification pendingEVENTpep-talk con ��� First US Peptide Convention · August 2026 · Anaheim CAFDAFDA advisory committee meetings scheduled: late July 2026

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Research Library

749 papers · 61 analysis articles

Research Analysis

Curated deep-dives into the latest peptide research

Papers Database

SS-31 improves post-cardiac arrest brain injury by inhibiting microglial ferroptosis and polarization.

Jiang Tangxing et al.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics2026
pubmedPreclinicalSS-31

Hexarelin promotes the survival of retinal ganglion cells after optic nerve transection.

Chow Kevin Bing ShuiIndian journal of pharmacology2026
pubmedPreclinicalHexarelinGrowth hormone secretagogue receptor type 1a agonist

LL-37-derived peptide shows promising antimicrobial potential against multidrug-resistance pathogens.

Asmamaw Demeke et al.European journal of medicinal chemistry2026
pubmedPreclinicalLL-37-derived peptideKF-22

Elamipretide (SS-31) promotes recovery by preserving mitochondrial bioenergetics and neural remodeling after spinal cord injury.

Song Zengtao et al.Neurochemistry international2026
pubmedPreclinicalElamipretideSS-31

Mechanisms of Anti-Oxidants, N-Acetylcysteine and Elamipretide (SS-31), on Ozone-Induced Airway Hyperresponsiveness and Mucus Hypersecretion.

Xie Meiqin et al.Lung2026
pubmedPreclinicalN-acetylcysteineElamipretide (SS-31)

Microenvironment-responsive injectable dynamic hydrogel for sequential antioxidant and tissue regeneration therapy of radiation-induced skin injury.

Yu Xiaorui et al.Bioactive materials2026
pubmedPreclinicalGHK-Cuantioxidant peptides

T cell receptor mimic CAR T cells targeting cathepsin G signal peptide.

Yan Jun et al.Leukemia2025
pubmedPreclinicalcathepsin G signal peptideCG1

Incretin triple agonist retatrutide (LY3437943) alleviates obesity-associated cancer progression.

Marathe Sandesh J et al.npj metabolic health and disease2025
pubmedPreclinicalretatrutideLY3437943

BAK and ARG Have Moisturizing, Anti-Inflammatory, Antioxidant, and Antioxidant Bioactivities, in the Zebrafish Model.

Jiang Xufeng et al.Journal of cosmetic dermatology2025
pubmedPreclinicalbakuchiolacetyl hexapeptide-8

Antagonist of Growth Hormone-Releasing Hormone Receptor MIA-690 Suppresses the Growth of Androgen-Independent Prostate Cancers.

Muñoz-Moreno Laura et al.International journal of molecular sciences2024
pubmedPreclinicalMIA-690GHRH-R antagonist

Exploring the role of GHRH antagonist MIA-602 in overcoming Doxorubicin-resistance in acute myeloid leukemia.

Gaumond Simonetta I et al.Oncotarget2024
pubmedPreclinicalMIA-602GHRH antagonist

Personalized neoantigen hydrogel vaccine combined with PD-1 and CTLA-4 double blockade elicits antitumor response in liver metastases by activating intratumoral CD8

Tang Shichuan et al.Journal for immunotherapy of cancer2024
pubmedPreclinicalneoantigen peptidesPoly(I:C)

Changes of Transcriptomic Activity in Rat Brain Cells under the Influence of Synthetic Adrenocorticotropic Hormone-Like Peptides.

Filippenkov Ivan B et al.Biochemistry. Biokhimiia2024
pubmedPreclinicalACTH(4-7)PGP (Semax)ACTH(6-9)PGP

MOTS-c regulates the ROS/TXNIP/NLRP3 pathway to alleviate diabetic cardiomyopathy.

Fu Yu et al.Biochemical and biophysical research communications2024
pubmedPreclinicalMOTS-c

New insight for SS‑31 in treating diabetic cardiomyopathy: Activation of mitoGPX4 and alleviation of mitochondria‑dependent ferroptosis.

Xiong Lie et al.International journal of molecular medicine2024
pubmedPreclinicalSS-31

Comprehensive dry eye therapy: overcoming ocular surface barrier and combating inflammation, oxidation, and mitochondrial damage.

Xia Yuanyou et al.Journal of nanobiotechnology2024
pubmedPreclinicalSS-31

KPV and RAPA Self-Assembled into Carrier-Free Nanodrugs for Vascular Calcification Therapy.

Zhang Li et al.Advanced healthcare materials2024
pubmedPreclinicalKPVRAPA

TERT activation targets DNA methylation and multiple aging hallmarks.

Shim Hong Seok et al.Cell2024
pubmedPreclinicalHumanTERT activator compound (TAC)MEK/ERK/AP-1 cascade

Ultrasensitive and Label-Free Detection of Copper Ions by GHK-Modified Asymmetric Nanochannels.

An Pengrong et al.Analytical chemistry2023
pubmedPreclinicalGHKDPCM

Age-related disruption of the proteome and acetylome in mouse hearts is associated with loss of function and attenuated by elamipretide (SS-31) and nicotinamide mononucleotide (NMN) treatment.

Whitson Jeremy A et al.GeroScience2022
pubmedPreclinicalelamipretide (SS-31)nicotinamide mononucleotide (NMN)

LL-37 transports immunoreactive cGAMP to activate STING signaling and enhance interferon-mediated host antiviral immunity.

Wei Xubiao et al.Cell reports2022
pubmedPreclinicalLL-37

Skin-adaptive film dressing with smart-release of growth factors accelerated diabetic wound healing.

Zhao Yingzheng et al.International journal of biological macromolecules2022
pubmedPreclinicalKPVEGF

Self-Cross-Linked Hydrogel of Cysteamine-Grafted γ-Polyglutamic Acid Stabilized Tripeptide KPV for Alleviating TNBS-Induced Ulcerative Colitis in Rats.

Sun Jie et al.ACS biomaterials science & engineering2021
pubmedPreclinicalKPVα-MSH

Whole-body senescent cell clearance alleviates age-related brain inflammation and cognitive impairment in mice.

Ogrodnik Mikolaj et al.Aging cell2021
pubmedPreclinical

Long-Lasting Stable Expression of Human LL-37 Antimicrobial Peptide in Transgenic Barley Plants

M. Mirzaee et al.Antibiotics2021
S2PreclinicalLL-37human cathelicidin

IGF-1 infusion to fetal sheep increases organ growth but not by stimulating nutrient transfer to the fetus.

Stremming Jane et al.American journal of physiology. Endocrinology and metabolism2021
pubmedPreclinicalIGF-1LR3 IGF-1

Correction of Lipid Metabolism Disorders in Diabetes Mellitus with Peptide Drugs.

Elagina A A et al.Bulletin of experimental biology and medicine2020
pubmedPreclinicaldeltalicinSemax

Peptide ACTH

Severyanova L A et al.Bulletin of experimental biology and medicine2020
pubmedPreclinicalACTH4-7-PGPSemax

Inhibition of activin-like kinase 4/5 attenuates cancer cachexia associated muscle wasting.

Levolger S et al.Scientific reports2019
pubmedPreclinicalSB431542GW788388

The mitochondrial-derived peptide MOTS-c is a regulator of plasma metabolites and enhances insulin sensitivity.

Kim Su-Jeong et al.Physiological reports2019
pubmedPreclinicalMOTS-c

Effects of Diclofenac, L-NAME, L-Arginine, and Pentadecapeptide BPC 157 on Gastrointestinal, Liver, and Brain Lesions, Failed Anastomosis, and Intestinal Adaptation Deterioration in 24 Hour-Short-Bowel Rats

N. Lojo et al.PLoS ONE2016
S2PreclinicalBPC 157L-NAME