REGULATORYRFK Jr.: 14 peptides returning to Category 1 — FDA advisory committee July 2026TRENDINGHexarelin: ↑↑ Surging ��� Trends score 100 as of May 2026UPDATESemaglutide and tirzepatide compounding ended — shortage resolved Feb/May 2025REGULATORYBPC-157, TB-500, thymosin alpha-1, CJC-1295, ipamorelin: expected Category 1 reclassification pendingEVENTpep-talk con ��� First US Peptide Convention · August 2026 · Anaheim CAFDAFDA advisory committee meetings scheduled: late July 2026REGULATORYRFK Jr.: 14 peptides returning to Category 1 — FDA advisory committee July 2026TRENDINGHexarelin: ↑↑ Surging ��� Trends score 100 as of May 2026UPDATESemaglutide and tirzepatide compounding ended — shortage resolved Feb/May 2025REGULATORYBPC-157, TB-500, thymosin alpha-1, CJC-1295, ipamorelin: expected Category 1 reclassification pendingEVENTpep-talk con ��� First US Peptide Convention · August 2026 · Anaheim CAFDAFDA advisory committee meetings scheduled: late July 2026

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Research Library

749 papers · 61 analysis articles

Research Analysis

Curated deep-dives into the latest peptide research

Papers Database

Coadministered Cagrilintide and Semaglutide in Adults with Overweight or Obesity.

Garvey W Timothy et al.The New England journal of medicine2025
pubmedRCT

Oral Semaglutide at a Dose of 25 mg in Adults with Overweight or Obesity.

Wharton Sean et al.The New England journal of medicine2025
pubmedRCT

Cagrilintide-Semaglutide in Adults with Overweight or Obesity and Type 2 Diabetes.

Davies Melanie J et al.The New England journal of medicine2025
pubmedRCT

Once-weekly semaglutide 7·2 mg in adults with obesity (STEP UP): a randomised, controlled, phase 3b trial.

Wharton Sean et al.The lancet. Diabetes & endocrinology2025
pubmedRCT

Semaglutide in Adults with Type 1 Diabetes and Obesity.

Shah Viral N et al.NEJM evidence2025
pubmedRCT

Semaglutide and walking capacity in people with symptomatic peripheral artery disease and type 2 diabetes (STRIDE): a phase 3b, double-blind, randomised, placebo-controlled trial.

Bonaca Marc P et al.Lancet (London, England)2025
pubmedRCT

First-in-human safety, tolerability, and pharmacokinetic results of DFV890, an oral low-molecular-weight NLRP3 inhibitor.

Gatlik Ewa et al.Clinical and translational science2024
pubmedRCT

Triple hormone receptor agonist retatrutide for metabolic dysfunction-associated steatotic liver disease: a randomized phase 2a trial.

Sanyal Arun J et al.Nature medicine2024
pubmedRCT

A randomized placebo-controlled trial of nicotinamide riboside in older adults with mild cognitive impairment.

Orr Miranda E et al.GeroScience2024
pubmedRCT

Safety and immunogenicity of a synthetic nanoparticle-based, T cell priming peptide vaccine against dengue in healthy adults in Switzerland: a double-blind, randomized, vehicle-controlled, phase 1 study.

Miauton Alix et al.EBioMedicine2024
pubmedRCT

Deucrictibant for angioedema due to acquired C1-inhibitor deficiency: A randomized-controlled trial.

Petersen Remy S et al.The Journal of allergy and clinical immunology2024
pubmedRCT

Acute salivary antimicrobial peptide secretion response to different exercise intensities and durations.

Ito Reita et al.American journal of physiology. Regulatory, integrative and comparative physiology2024
pubmedRCT

Obesity, Cardiovascular Disease, and the Promising Role of Semaglutide: Insights from the SELECT Trial.

Irfan HamzaCurrent problems in cardiology2024
pubmedRCTHumanHigh QualitySemaglutideGLP-1 receptor agonist

Safety, Tolerability, Bioavailability, and Biological Activity of Inhaled Interferon-α2b in Healthy Adults: The IN

Garcia-Huidobro Diego et al.Clinical drug investigation2023
pubmedRCT

Triple-Hormone-Receptor Agonist Retatrutide for Obesity - A Phase 2 Trial.

Jastreboff Ania M et al.The New England journal of medicine2023
pubmedRCT

Combination of exercise and GLP-1 receptor agonist treatment reduces severity of metabolic syndrome, abdominal obesity, and inflammation: a randomized controlled trial.

Sandsdal Rasmus M et al.Cardiovascular diabetology2023
pubmedRCT

Safety and Efficacy of Liraglutide, 3.0 mg, Once Daily vs Placebo in Patients With Poor Weight Loss Following Metabolic Surgery: The BARI-OPTIMISE Randomized Clinical Trial.

Mok Jessica et al.JAMA surgery2023
pubmedRCT

Collagen peptides supplementation improves function, pain, and physical and mental outcomes in active adults.

Kviatkovsky Shiloah A et al.Journal of the International Society of Sports Nutrition2023
pubmedRCT

The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial.

Yi Lin et al.GeroScience2023
pubmedRCT

Efficacy and Safety of Aflapin®, a Novel

Karlapudi Vasu et al.Journal of the American Nutrition Association2023
pubmedRCT

Effect of the glucagon-like peptide-1 receptor agonist liraglutide, compared to caloric restriction, on appetite, dietary intake, body fat distribution and cardiometabolic biomarkers: A randomized trial in adults with obesity and prediabetes.

Silver Heidi J et al.Diabetes, obesity & metabolism2023
pubmedRCTHumanHigh Qualityglucagon-like peptide-1 receptor agonistliraglutide

Immune enhancement in patients with predicted severe acute necrotising pancreatitis: a multicentre double-blind randomised controlled trial.

Ke Lu et al.Intensive care medicine2022
pubmedRCT

Prespecified and Integrated Subgroup Analyses from the RECONNECT Phase 3 Studies of Bremelanotide.

Simon James A et al.Journal of women's health (2002)2022
pubmedRCT

Safety Profile of Bremelanotide Across the Clinical Development Program.

Clayton Anita H et al.Journal of women's health (2002)2022
pubmedRCTHumanHigh QualityBremelanotide

Effect of Weekly Subcutaneous Semaglutide vs Daily Liraglutide on Body Weight in Adults With Overweight or Obesity Without Diabetes: The STEP 8 Randomized Clinical Trial.

Rubino Domenica M et al.JAMA2022
pubmedRCTHumanHigh Qualitysemaglutideliraglutide

Dual GIP and GLP-1 Receptor Agonist Tirzepatide Improves Beta-cell Function and Insulin Sensitivity in Type 2 Diabetes.

Thomas Melissa K et al.The Journal of clinical endocrinology and metabolism2021
pubmedRCT

Once-Weekly Semaglutide in Adults with Overweight or Obesity.

Wilding John P H et al.The New England journal of medicine2021
pubmedRCT

Effect of Subcutaneous Semaglutide vs Placebo as an Adjunct to Intensive Behavioral Therapy on Body Weight in Adults With Overweight or Obesity: The STEP 3 Randomized Clinical Trial.

Wadden Thomas A et al.JAMA2021
pubmedRCT

Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial.

Rubino Domenica et al.JAMA2021
pubmedRCTHumanHigh QualitysemaglutideGLP-1 receptor agonist

Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1): a double-blind, randomised, phase 3 trial.

Rosenstock Julio et al.Lancet (London, England)2021
pubmedRCTHumanHigh QualitytirzepatideGIP receptor agonist

Safety and immunogenicity of a mosquito saliva peptide-based vaccine: a randomised, placebo-controlled, double-blind, phase 1 trial.

Manning Jessica E et al.Lancet (London, England)2020
pubmedRCT

Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials.

Kingsberg Sheryl A et al.Obstetrics and gynecology2019
pubmedRCT

Responder Analyses from a Phase 2b Dose-Ranging Study of Bremelanotide.

Althof Stanley et al.The journal of sexual medicine2019
pubmedRCTHumanHigh QualitybremelanotideHSDD

Neonatal Fc receptor antagonist efgartigimod safely and sustainably reduces IgGs in humans.

Ulrichts Peter et al.The Journal of clinical investigation2018
pubmedRCT

Effects of Meditation and Music-Listening on Blood Biomarkers of Cellular Aging and Alzheimer's Disease in Adults with Subjective Cognitive Decline: An Exploratory Randomized Clinical Trial.

Innes Kim E et al.Journal of Alzheimer's disease : JAD2018
pubmedRCT

Efficacy and safety of LY3298176, a novel dual GIP and GLP-1 receptor agonist, in patients with type 2 diabetes: a randomised, placebo-controlled and active comparator-controlled phase 2 trial.

Frias Juan Pablo et al.Lancet (London, England)2018
pubmedRCT

LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept.

Coskun Tamer et al.Molecular metabolism2018
pubmedRCT