REGULATORYRFK Jr.: 14 peptides returning to Category 1 — FDA advisory committee July 2026UPDATESemaglutide and tirzepatide compounding ended — shortage resolved Feb/May 2025REGULATORYBPC-157, TB-500, thymosin alpha-1, CJC-1295, ipamorelin: expected Category 1 reclassification pendingFDAFDA advisory committee meetings scheduled: late July 2026RESEARCHTranslational Health Research Into Vascular and Neurocognitive Effects of Weight Loss [NCT07592546]RESEARCHA Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes) [NCT07165028]RESEARCHTirzepatide in the Treatment of Endometrial Cancer [NCT07605247]RESEARCHA Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes During Ramadan [NCT06635057]RESEARCHA Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide [NCT06897475]RESEARCHA Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature [NCT06382155]RESEARCHMetabolic Effects of Angiotensin-(1-7) [NCT02646475]RESEARCHMulti-Site Trial of Tirzepatide for Smoking Cessation [NCT07602699]RESEARCHEvaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder [NCT06651177]NEWSOorja, run by Acceleron veterans, launches to make new fibrosis drugsREGULATORYRFK Jr.: 14 peptides returning to Category 1 — FDA advisory committee July 2026UPDATESemaglutide and tirzepatide compounding ended — shortage resolved Feb/May 2025REGULATORYBPC-157, TB-500, thymosin alpha-1, CJC-1295, ipamorelin: expected Category 1 reclassification pendingFDAFDA advisory committee meetings scheduled: late July 2026RESEARCHTranslational Health Research Into Vascular and Neurocognitive Effects of Weight Loss [NCT07592546]RESEARCHA Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes) [NCT07165028]RESEARCHTirzepatide in the Treatment of Endometrial Cancer [NCT07605247]RESEARCHA Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes During Ramadan [NCT06635057]RESEARCHA Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide [NCT06897475]RESEARCHA Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature [NCT06382155]RESEARCHMetabolic Effects of Angiotensin-(1-7) [NCT02646475]RESEARCHMulti-Site Trial of Tirzepatide for Smoking Cessation [NCT07602699]RESEARCHEvaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder [NCT06651177]NEWSOorja, run by Acceleron veterans, launches to make new fibrosis drugs

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749 papers · 104 analysis articles

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Efficacy and Safety of Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss Among Adults Without Diabetes : A Systematic Review of Randomized Controlled Trials.

Moiz Areesha et al.Annals of internal medicine2025
pubmedSystematic Review

Echinocandins Pharmacokinetics: A Comprehensive Review of Micafungin, Caspofungin, Anidulafungin, and Rezafungin Population Pharmacokinetic Models and Dose Optimization in Special Populations.

Albanell-Fernández MartaClinical pharmacokinetics2025
pubmedSystematic ReviewHumanHigh Qualitymicafungincaspofungin

Efficacy and safety of retatrutide for the treatment of obesity: a systematic review of clinical trials.

Misra Saurav et al.Journal of basic and clinical physiology and pharmacology2025
pubmedSystematic ReviewHumanHigh Qualityretatrutideglucagon receptor agonist

A systematic review of the effect of semaglutide on lean mass: insights from clinical trials.

Bikou Alexia et al.Expert opinion on pharmacotherapy2024
pubmedSystematic Review

Comprehensive Review of the Safety and Efficacy of Thymosin Alpha 1 in Human Clinical Trials.

Dinetz Elliot et al.Alternative therapies in health and medicine2024
pubmedSystematic ReviewHumanHigh QualityThymosin Alpha 1Tα1

Effects of GLP-1 receptor agonists on neurological complications of diabetes.

García-Casares Natalia et al.Reviews in endocrine & metabolic disorders2023
pubmedSystematic Review

Adverse drug reactions of GLP-1 agonists: A systematic review of case reports.

Shetty Rashmi et al.Diabetes & metabolic syndrome2022
pubmedSystematic Review

Tirzepatide: A Systematic Update.

Forzano Imma et al.International journal of molecular sciences2022
pubmedSystematic ReviewHumanHigh QualityTirzepatideGIP

Peptide Regulation of Gene Expression: A Systematic Review.

Khavinson Vladimir Khatskelevich et al.Molecules (Basel, Switzerland)2021
pubmedSystematic ReviewHumanHigh Qualitygene expression regulationDNA methylation

NAD+ therapy in age-related degenerative disorders: A benefit/risk analysis.

Braidy Nady et al.Experimental gerontology2020
pubmedSystematic Review

Bremelanotide: New Drug Approved for Treating Hypoactive Sexual Desire Disorder.

Mayer Danielle et al.The Annals of pharmacotherapy2020
pubmedSystematic Review