REGULATORYRFK Jr.: 14 peptides returning to Category 1 — FDA advisory committee July 2026UPDATESemaglutide and tirzepatide compounding ended — shortage resolved Feb/May 2025REGULATORYBPC-157, TB-500, thymosin alpha-1, CJC-1295, ipamorelin: expected Category 1 reclassification pendingFDAFDA advisory committee meetings scheduled: late July 2026RESEARCHA Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature [NCT06382155]RESEARCHMetabolic Effects of Angiotensin-(1-7) [NCT02646475]RESEARCHEvaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder [NCT06651177]RESEARCHMulti-Site Trial of Tirzepatide for Smoking Cessation [NCT07602699]RESEARCHA Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide [NCT06897475]RESEARCHTranslational Health Research Into Vascular and Neurocognitive Effects of Weight Loss [NCT07592546]RESEARCHTirzepatide in the Treatment of Endometrial Cancer [NCT07605247]RESEARCHA Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes During Ramadan [NCT06635057]RESEARCHA Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes) [NCT07165028]NEWSOorja, run by Acceleron veterans, launches to make new fibrosis drugsREGULATORYRFK Jr.: 14 peptides returning to Category 1 — FDA advisory committee July 2026UPDATESemaglutide and tirzepatide compounding ended — shortage resolved Feb/May 2025REGULATORYBPC-157, TB-500, thymosin alpha-1, CJC-1295, ipamorelin: expected Category 1 reclassification pendingFDAFDA advisory committee meetings scheduled: late July 2026RESEARCHA Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature [NCT06382155]RESEARCHMetabolic Effects of Angiotensin-(1-7) [NCT02646475]RESEARCHEvaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder [NCT06651177]RESEARCHMulti-Site Trial of Tirzepatide for Smoking Cessation [NCT07602699]RESEARCHA Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide [NCT06897475]RESEARCHTranslational Health Research Into Vascular and Neurocognitive Effects of Weight Loss [NCT07592546]RESEARCHTirzepatide in the Treatment of Endometrial Cancer [NCT07605247]RESEARCHA Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes During Ramadan [NCT06635057]RESEARCHA Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes) [NCT07165028]NEWSOorja, run by Acceleron veterans, launches to make new fibrosis drugs

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Researcher

William Mitch

Baylor College of Medicine

About

Addison Mitchell McConnell III ( mə-KON-əl; born February 20, 1942) is an American politician and attorney serving as the senior United States senator from Kentucky, a seat he has held since 1985. McConnell is in his seventh Senate term and is the longest-serving senator in Kentucky history. He served from 2007 to 2025 as the leader of the Senate Republican Conference, including two stints as minority leader (2007 to 2015 and 2021 to 2025), and was majority leader from 2015 to 2021, making him the longest-serving Senate party leader in U.S. history. McConnell holds conservative political positions, although he was known as a pragmatist and a moderate Republican early in his political career. He led opposition to stricter campaign finance laws, culminating in the U.S. Supreme Court decision Citizens United v. FEC, which partially overturned the Bipartisan Campaign Reform Act (McCain-Feingold) in 2010. McConnell worked to withhold Republican support for major presidential initiatives during the Obama administration, making frequent use of the filibuster, and blocked many of President Barack Obama's judicial nominees, including Supreme Court nominee Merrick Garland. During the first Trump administration, the Senate Republican majority under McConnell's leadership passed the Tax Cuts and Jobs Act of 2017, the Economic Growth, Regulatory Relief and Consumer Protection Act in 2018, the First Step Act, and the Great American Outdoors Act, and confirmed a record number of federal appeals court judges during a president's first two years. McConnell invoked the nuclear option to eliminate the 60-vote requirement to end a filibuster for Supreme Court nominations, after his predecessor Harry Reid had eliminated the filibuster for all other presidential nominations; Trump subsequently won Supreme Court confirmation battles over Neil Gorsuch, Brett Kavanaugh and Amy Coney Barrett. While supportive of most of Trump's domestic and foreign policies, McConnell criticized Trump's at