REGULATORYRFK Jr.: 14 peptides returning to Category 1 — FDA advisory committee July 2026UPDATESemaglutide and tirzepatide compounding ended — shortage resolved Feb/May 2025REGULATORYBPC-157, TB-500, thymosin alpha-1, CJC-1295, ipamorelin: expected Category 1 reclassification pendingFDAFDA advisory committee meetings scheduled: late July 2026RESEARCHA Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature [NCT06382155]RESEARCHMetabolic Effects of Angiotensin-(1-7) [NCT02646475]RESEARCHEvaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder [NCT06651177]RESEARCHMulti-Site Trial of Tirzepatide for Smoking Cessation [NCT07602699]RESEARCHA Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide [NCT06897475]RESEARCHTranslational Health Research Into Vascular and Neurocognitive Effects of Weight Loss [NCT07592546]RESEARCHTirzepatide in the Treatment of Endometrial Cancer [NCT07605247]RESEARCHA Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes During Ramadan [NCT06635057]RESEARCHA Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes) [NCT07165028]NEWSOorja, run by Acceleron veterans, launches to make new fibrosis drugsREGULATORYRFK Jr.: 14 peptides returning to Category 1 — FDA advisory committee July 2026UPDATESemaglutide and tirzepatide compounding ended — shortage resolved Feb/May 2025REGULATORYBPC-157, TB-500, thymosin alpha-1, CJC-1295, ipamorelin: expected Category 1 reclassification pendingFDAFDA advisory committee meetings scheduled: late July 2026RESEARCHA Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature [NCT06382155]RESEARCHMetabolic Effects of Angiotensin-(1-7) [NCT02646475]RESEARCHEvaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder [NCT06651177]RESEARCHMulti-Site Trial of Tirzepatide for Smoking Cessation [NCT07602699]RESEARCHA Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide [NCT06897475]RESEARCHTranslational Health Research Into Vascular and Neurocognitive Effects of Weight Loss [NCT07592546]RESEARCHTirzepatide in the Treatment of Endometrial Cancer [NCT07605247]RESEARCHA Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes During Ramadan [NCT06635057]RESEARCHA Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes) [NCT07165028]NEWSOorja, run by Acceleron veterans, launches to make new fibrosis drugs

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Results & Progress
9

Oxytocin — 12 Week Progress Report

Jesse Cortez·about 1 month ago
Twelve weeks in with Oxytocin and I wanted to give a thorough progress report. I have been tracking metrics closely since day one. The first noticeable change came around week 2-3: improved sleep quality. I went from waking up 2-3 times per night to sleeping through consistently. My sleep tracker confirmed what I was feeling — deep sleep increased by about 25 percent. By week 6, the recovery improvements were undeniable. Soreness after heavy training sessions dropped from 2-3 days to about 1 day. I was able to increase training frequency from 4 to 5 days per week without feeling overtrained. Body composition shifted gradually. I did not see dramatic scale changes, but my waist measurement dropped by about an inch while my weight stayed roughly the same. Clothes fit differently. A DEXA scan would have been nice but was not in my budget. Energy levels improved noticeably in the afternoon slump period. I used to rely on coffee around 2-3pm but have not needed it since about week 4. Overall I would rate Oxytocin as genuinely effective for my goals. Not a miracle but a meaningful improvement across multiple health markers.

Comments (4)

Zev BrennanDEMO·about 1 month ago

This thread has been incredibly helpful for understanding Oxytocin. I have been on the fence about starting for months and reading detailed real-world experiences like these has been more useful than any blog post or article I have found. The fact that most reports here are moderate rather than extreme actually increases my confidence.

3
Shiloh JacobsDEMO·about 1 month ago

One thing I wish more Oxytocin discussions covered is the discontinuation experience. What happens when you stop? In my case, the benefits gradually faded over about 3-4 weeks after stopping. Sleep was the first thing to return to baseline. Recovery improvements lasted a bit longer. Worth knowing for planning protocol duration.

4
Peyton FosterDEMO·about 1 month ago

Great point about bloodwork. I ran comprehensive panels at baseline, 6 weeks, and 12 weeks during my Oxytocin protocol. The most informative markers for me were inflammatory markers and IGF-1 levels. Would strongly recommend anyone running Oxytocin to invest in proper monitoring.

5
Harley HaleDEMO·about 1 month ago

The timeline you describe is spot on with my Oxytocin experience. I also want to emphasize the importance of injection technique. When I switched from 30-gauge to 29-gauge needles and slowed my injection speed, the site irritation essentially disappeared. Small details make a big difference in compliance.

2

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